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Continuing with the overhaul of its transport sector to reduce air pollution and congestion creates an investment opportunity of $2 billion in public transport and $7 billion in electric vehicles. Implementing efficiency standards in the 50,000 new homes expected annually to 2030 will contribute to the $18 billion investment opportunity in green buildings. Executive Summary xiii Cities will be at the epicenter of climate action to limit global warming to 1. Cities also have a range of adaptation options they can use to reduce the risks of sea level rise (such as coastal defense and hardening) and the risks to health, livelihoods, food, water, and economic growth in urban areas (such as green infrastructure, sustainable land use and planning, and sustainable water management). To meet the urgent challenges faced by their residents on a daily basis, cities are defining their own development trajectories, and the paths they take will have dramatic consequences. Their decisions on what to prioritize politically, on what to build, and how to build it will reverberate globally, with significant implications for millions of people and for the planet as a whole. By 2030, the world is projected to have 43 megacities, each with more than 10 million inhabitants, and most of them in developing regions. However, the fastest-growing cities are those with fewer than 1 million inhabitants, many of them in Asia and Africa. Urban policy decisions made by 2020 could account for up to a third of the remaining global carbon budget that is not already "locked in" by past decisions. Ensuring an integrated approach to urban planning and investing in climate-smart city projects will be essential. Through the One Planet Charter, 815 cities from 65 countries, including 25 emerging markets, made commitments where the private sector can play a key role in supporting implementation. Through this initiative, cities are starting to develop Paris Agreement Compatible Climate Action Plans. Seven C40 cities have already published climate change strategies designed to deliver on the 1. The ability of cities to make such commitments and act on them is determined by their access to data about sector-specific emissions and resource potential, which is necessary for them to set their mitigation goals and identify reduction opportunities. Surging Climate Commitments by Cities Recognizing the opportunity to address both development priorities and the climate challenge, 440 mayors and subnational leaders pledged to deliver up to 3. Cities in Africa, Latin America, and South Asia have accelerated their commitments to tackle climate change in the last two years. Through the Global Covenant of Mayors, over 9,000 cities have committed to registering and tracking their climate-related actions and emissions, with many using a C R O S S- C U T T I N G T H E M E Data: A Critical Lynchpin to Climate Action the Environmental Insights Explorer-a new tool to assist cities with developing a greenhousegas emissions inventory-was announced at the 2018 Global Climate Action Summit in San Francisco. It is the first result of a new long-term partnership between the Global Covenant of Mayors, Bloomberg Philanthropies, and Google through the Innovate4Cities Accelerator. Almost two-thirds of the Global Covenant of Mayors member cities have yet to develop a greenhouse-gas emission inventory. The tool is a new addition to the suite of solutions that will assist with this, and over time will expand its coverage to include thousands of cities globally, allowing local governments to instantly and freely access the data they need to develop city greenhouse-gas emissions inventories-a process that used to cost a megacity between $250,000 and $700,000 and take up to two years to complete. The tool will be a web-based application that allows cities to freely explore aggregated data and plan climate action. The partnership is working to quickly expand its global coverage, aiming to have high-quality data online for the next 50 cities by the end of 2018 and adding another 2,000 cities in 2019, with a focus on emerging economies. Cities are invited to provide comments and feedback, and nominate their city to be next on the site. The Innovate4Cities agenda is a starting point for the Global Covenant of Mayors and all the cities it represents.

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Physical Capacity 84 Other benefits of exercise in breast cancer patients Table 23 impotence herbs purchase levitra super active 40mg with mastercard. Muscular Strength: 6 resistance and aerobicbased exercise trials for post-treatment breast cancer survivors assessed changes in both upper and lower body muscle strength have observed significant positive effects impotence after 50 cheap 40mg levitra super active visa. Half of the studies showing statistically significant positive effects related to body size or body composition erectile dysfunction treatment injection discount levitra super active 40mg line. Type: Supervised program of weights Time: 6 weeks (If a break is taken erectile dysfunction doctors long island order generic levitra super active from india, back off the level of resistance by 2 wk worth for every week of no exercise. Reversibility: it is important to encourage life-long changes in exercise habits, rather than merely performing a set 8 week intervention. Critical Appraisal for Exercise Interventions Study Subjects Intervention Outcome measures Activity Adamsen et al 2009 Group 1 Control: 134 patients with a variety of cancer diagnosis, mean age 47. All female patients currently undergoing adjuvant therapy Group 1: Conventional Medical Treatment Group 2: Home based walking intervention and information booklet and video educating of exercise prescription Walking: 60-70% of max Heart Rate (No measure of intensity) 15 minute sessions progressed to 30 minutes as training progressed 5-6 times per week for as long as adjuvant treatment lasted. Trends towards increase in physical function and activity and 12 minute walking distance. Results effected by the fact that 38% of usual care group exercised and 28% of exercise group did not exercise. Intervention group showed benefits in physical and Random allocation: Yes Concealed allocation: Yes Baseline comparability: Yes Blind subjects: No 89 breast cancer, mean age 51. All Patients female currently undergoing adjuvant therapy 1 additional home based exercise session. Benefits were maintained at 6 month follow up with the exception of self reported physical activity. QoL was unchanged at 12 weeks but showed a statistically significant improvement at 6 months. Group 3: Resistance Exercise- Home Based weight bearing theraband exercise for major upper limb and lower limb muscle groups. Group 2: Flexibility stretching control group stretching Cervical and thoracic spine and upper and lower limbs. Group 3- Aerobic exercise Training, cycle ergometer, treadmill or elliptical training. Fatigue: prescribe low-to-moderate intensity, interval exercise and exercise when fatigue is at its lowest (De Paleviille et al 2007). Time barriers: hold exercise classes in venues accessible by public transport and timetable classes at times agreed on by participants (Markes et al 2006). Given improved screening, improved prognosis following diagnosis and the aging population, the number of people living with lung cancer in the community is growing (Granger et al 2011). Pre-Operative Programme Frequency 5 Times per week for until surgical intervention Intensity 60% of baseline peak aerobic capacity progressing to 65% and finally involving 1 interval session involving 30 seconds at peak aerobic capacity followed by a 60 seconds break for 15 minutes (Jones et al 2007) Post Operative Programme Frequency 8-14 weeks or duration of hospital stay prior to surgical intervention 8-14 weeks or duration of hospital stay prior to surgical intervention Intensity 60% of peak baseline power progressing to 70-80% peak power output. Other reports suggest that silicone implants can rupture and the saline contents seep out resulting in immune system diseases. Despite these reports there is a lack of strong evidence confirming these links and these implants continue to be used routinely. Types of Surgeries 1) One Stage Immediate Breast Reconstruction Surgery Performed with mastectomy. Reservations that immediate reconstruction can delay post-op therapy or subsequent surveillance for recurrence have been refuted by several studies. Benefits: Immediate reconstruction can offer technical, aesthetic and economical advantages. More comfortable in the case of implants as there is less need for expanding of underlying chest skin. Excess skin saved by skin sparring mastectomy can provide the most natural look and feel, which is lost in delayed non skin-sparring techniques. Although post-mastectomy radiation can result in increased complications due to reconstruction, the reconstruction is usually maintained. The skin post mastectomy is allowed to heal, an expander is placed under the chest wall skin and muscles and slowly expanded over a 6 month period. For tissue flap procedures delayed techniques, scar formation with resulting stiffening and contracture of the skin may distort the breast shape. The flap uses the rectus abdominis muscle as a channel for blood flow to supply the overlying subcutaneous fat and skin.

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The test checks the levels of your red blood cells impotence caused by diabetes cheap levitra super active, white blood cells and platelets erectile dysfunction when drunk cheap 40mg levitra super active overnight delivery. It helps the doctor gauge how much chemo you can tolerate at that particular time erectile dysfunction types purchase levitra super active on line. When your red cell count is too low impotence blood pressure generic levitra super active 40 mg visa, you may also have difficulty breathing or feel dizzy when you stand up quickly. Red blood cells live from three to four months in your body, so the effects of chemotherapy are likely to be minimal on this part of your blood. After you receive chemotherapy, the number of white cells in your blood may be low, making you susceptible to infections. If your platelet count falls with chemotherapy, you may bruise or bleed more easily. The durations of chemotherapy or radiation may be prolonged for some women or not for others. Understanding that this might occur, and allowing for flexibility in scheduling if it occurs, will make the process easier. Hormonal (Anti-Estrogen) Therapy Breast cancers are tested for whether they have receptors for the hormones estrogen and progesterone. Tamoxifen was the first anti-estrogen drug used in this setting and is still the main drug used for anti-estrogen treatment in premenopausal women. Aromatase inhibitors are now most often used in place of or sequentially with Tamoxifen in postmenopausal patients. Most of these drugs are given orally and are tolerated with few major side effects. The duration of therapy is generally between 5 and 10 years and is determined by the patient and her physician. Biologic Therapy Agents are used to attack specific targets critical to cancer growth and spread. Two agents currently used in the adjuvant setting are drugs called trastuzumab or Herceptin and pertuzumab or Perjeta. These are intravenous drugs, generally given with chemotherapy, then continued alone for a year. The development of new therapies is another indication of the progress being made in treating breast cancer early to prevent recurrence. But you should never replace any part of your regular treatment (surgery, chemotherapy, radiation, hormonal treatment) with something else. Conventional medicine has been proven to be safe and effective by numerous scientific studies. Complementary medicine includes techniques such as acupuncture, herbal medicine, massage, support groups, and yoga. For many people diagnosed with breast cancer, complementary medicine helps to relieve symptoms, ease treatment side effects, and improve quality of life. Complementary therapies are added to or used to "complement" conventional medicine. Complementary medicine can be combined or integrated with conventional medical treatment, and is thus also called "integrative medicine. For example, studies have found that up to 80% of breast cancer survivors have used at least one complementary technique. To help doctors and patients understand which complementary therapies are safe and effective for people diagnosed with breast cancer, the Society for Integrative Oncology released guidelines that make recommendations about more than 80 complementary therapies. Meditation, yoga, and relaxation with imagery are recommended for routine use for common conditions, including anxiety and mood disorders (Grade A).

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We reached Paddington at seven, and drove direct to the restaurant I have before described, where we partook of a light meal, left Montmorency, together with suggestions for a supper to be ready at half-past ten, and then continued our way to Leicester Square. On our presenting ourselves at the paybox we were gruffly directed to go round to Castle Street, and were informed that we were half-an-hour behind our time. Our fine bronzed countenances and picturesque clothes were followed round the place with admiring gaze. We adjourned soon after the first ballet, and wended our way back to the restaurant, where supper was already awaiting us. For about ten days we seemed to have been living, more or less, on nothing but cold meat, cake, and bread and jam. It had been a simple, a nutritious diet; but there had been nothing exciting about it, and the odour of Burgundy, and the smell of French sauces, and the sight of clean napkins and long loaves, knocked as a very welcome visitor at the door of our inner man. Then Harris, who was sitting next the window, drew aside the curtain and looked out upon the street. It glistened darkly in the wet, the dim lamps flickered with each gust, the rain splashed steadily into the puddles and trickled down the water- spouts into the running gutters. A few soaked wayfarers hurried past, crouching beneath their dripping umbrellas, the women holding up their skirts. This large ledger provided 11 columns for information referring to each interment located across two side-by-side pages. This material is presented for internet access by linking two pdf files, one from each original page, expanded to include additional information found in other sources. The alphabetical file begins on page 51 and has bookmarks to help locate the recorded personal information from the left page of the original ledger. Yet, living conditions for most citizens remain dismal as a result of inequitable distribution of resource revenues. The steady flow of natural resource revenues funds the patronage and security structures these governments rely on to remain in power without popular support. States heavily reliant on the export of oil and minerals, moreover, face a greater risk of civil conflict than their resource-poor counterparts. If accountably governed, natural resource wealth could be a boon to a society, enabling valuable investments in infrastructure, human capital, social services, and other public goods. With their technical expertise and financial resources, international corporations can be a vital component in the resource management equation in Africa by helping a country get its resources to the market and recovering a higher return for the public than would otherwise be the case. These entrepreneurs thrive in environments where governments are financially desperate or diplomatically isolated, oversight institutions are weak, and civil society is stifled. These predatory corporations are not merely bystanders conducting business as usual in an unsavory environment. They often proactively empower unaccountable leaders and frequently benefit directly from conflict and political crises. The potential return for these investors is enormous, compared to the marginal downside of a deal that falls through. With the right connections and willingness to operate amid relative chaos, these companies can make a fortune from resource-rich fragile states. This report examines these linkages by tracking the practices of one group of investors that has been particularly active on the continent since the early 2000s: a Hong Kong-based consortium known as the 88 Queensway Group. Cultivating relationships with high-level government officials in politically isolated resource-rich states through infusions of cash, promises of billions of dollars in infrastructural development, and support for the security sector, Queensway has been able to gain access to major oil and mining concessions across Africa. Starting in Angola in 2003, Queensway has been engaged in the extractive industries in at least nine African countries, including Guinea, Madagascar, Tanzania, and Zimbabwe. Promised high-profile infrastructure construction projects regularly fail to materialize. Allegations of corruption among senior government officials who control natural resource contracts are widespread. Reputable extractive firms are cut out of the market, undermining the long-term health of the resource sector. And unaccountable governments are able to persist, propped up by the infusion of financial and material support to the regimes in power. Transactions involving the Group have been the subject of criticism by journalists, watchdog groups, government officials, and lawmakers in numerous countries.

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Bright noted erectile dysfunction insurance coverage cheap 40 mg levitra super active with visa, "For centuries skeptics have claimed that the Bible is filled with historical errors erectile dysfunction age 29 purchase 40 mg levitra super active amex. They have pointed to several biblical accounts erectile dysfunction treatment austin tx order 40mg levitra super active amex, particularly in the Old Testament erectile dysfunction treatment options natural buy cheap levitra super active, where archeology contradicted the Bible. In many cases scientists have been proven to be inaccurate and the Bible has been shown to be trustworthy and reliable. Bright also pointed out: "The reliability of the Bible is seen in the amazing fulfillment of Old Testament prophecy in the New Testament. Scholars estimate we can find approximately twenty-five hundred prophecies in the Bible. But the odds that 2000 all two thousand prophecies could have been fulfilled by chance is less than one in 10 (that is one with two thousand zeros after it)! Barton Payne, Encyclopedia of Biblical Prophecy: the Complete Guide to Scriptural Predictions and Their Fulfillment (New York: Harper & Row, 1973). Pat Zukeran confirms this finding in his article "Archaeology and the Old Testament. Through these scribes and other events, God has preserved His Word through the centuries. Bright noted that this discovery was one ofthe "most important factors supporting the accuracy of the Old Testament. See also Laurie Copans, "Ancient Jewish Tablet Found" [on-line]; accessed 29 July 2005; available from They even devised elaborate systems for numbering every letter and word; if a scribe was offby even one letter, they would destroy the whole manuscript. Bright also said, "Over the years, archaeologists have found thousands of manuscripts of bits of the New Testament and even some complete copies. By comparing these, we can get very close to what the New Testament writers originally wrote. Some of these copies are dated less than 100 years after the original gospel or letter was written. For an idea of how good this evidence is, compare the New Testament with other writings that are about as old as the New Testament. For example, Julius Caesar wrote a book called the Gallic War about 50 years before Christ was born. Yet, we do have nine or ten copies, and the earliest of these was made about 900 years after the original. The 5 percent of variation consisted chiefly of obvious slips of the pen and variations in spelling. However, miracles can be either a stumbling block or an encouragement for one coming to ChriSt. He pointed out, "In addition to the revolutionary message He proclaimed, the miracles Jesus performed stand as a testimony to His true person. They were not capricious demonstrations of brute power, but were acts of a loving God, anxious to reveal His benevolent character to man. William Lane Craig aptly stated, "Fortunately, the Christian faith does not call for us to put our minds on the shelf, to fly in the face of common sense and history, or to make a leap of faith into the dark. The rational person, fully apprised of the evidence, can confidently believe that on that first Easter morning a 223Thid. For a tool for building a defense in support ofthe validity of miracles in the Bible, see C. Lewis, Miracles: How God Intervenes in Nature and Human Affairs (New York: Macmillan, 1960). Nash, Faith & Reason: Searchingfor a Rational Faith (Grand Rapids: Zondervan, 1988), and Norman L. Geisler, Miracles and the Modern Mind: A Defense of Biblical Miracles (Grand Rapids: Baker, 1992). He noted, "As a young skeptic, I had difficulty believing in the resurrection, for I could not believe in the supernatural. Bright continued, "Without the certainty of His resurrection, we would come to the end ofthis life without hope, with nothing to anticipate except despair and doubt.